Depression 15 Nov, 2021 Read Time: 1 min

Functional impact of depression

In addition to dysfunction across domains of cognition, depression also produces wider functional impairments in daily life.1 In fact, depression is ranked as the leading cause of disability worldwide, and is also a major contributor to the global burden of disease.2 Functional disability in daily activities is one of the most important consequences of depression, yet it is also one of the least understood.1

Depression impacts patients in the workplace, increasing both presenteeism (loss of productivity due to attendance despite illness) and absenteeism (failure to attend work due to illness), which in severe cases can result in cessation of employment.3 Abilities to maintain household responsibilities and manage finances can also decline, in addition to reduced quantity and quality of social relationships and community ties.1

 

References

  1. Jaeger J et al. Neurocognitive deficits and disability in major depressive disorder. Psychiatry Res 2006; 145(1): 39-48.
  2. Depression Factsheet. WHO. Available at: http://www.who.int/mediacentre/factsheets/fs369/en/. Accessed August 2015.
  3. Lerner D, Henke RM. What does research tell us about depression, job performance and work productivity? J Occup Environ Med 2008; 50(4): 401-410.
  4. Papakostas GI. Cognitive symptoms in patients with major depressive disorder and their implications for clinical practice. J Clin Psychiatry 2014; 75(1): 8-14.
  5. Trivedi MH et al. Cognitive dysfunction in unipolar depression: implications for treatment. J Affect Discord 2014; 152-154: 19-27.
  6. Majer M et al. Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders. Psychol Med 2004; 34(8): 1453-63.
  7. Paykel ES et al. Partial remission, residual symptoms, and relapse in depression. Dialogues Clin Neurosci 2008; 10: 431-437.